Art. 144 of Law 16-92 establishes that the administrators, managers, directors and other persons exercising administrative or management functions must preferably be of Dominican nationality. On the other hand, Art. 135 establishes that at least 80% of the total number of workers of a company must be composed of Dominicans. Art. 136 establishes that the salaries received by the Dominican workers of a company must amount, as a whole, to at least 80% of the value corresponding to the payment of all the personnel. Exempted from the provisions of this article are the salaries received by workers who perform technical, managerial or directorial tasks.

According to Art. 148 of Law No. 20-00, when the applicant or the holder of an industrial property right has its domicile or headquarters outside the Dominican Republic, it must have a representative domiciled in the country who can be notified of all resolutions, correspondence, writings and any other documentation emanating from the National Office for Industrial Property.

The Dominican Republic is a party to the Patent Cooperation Treaty (PCT).

The Dominican Republic has a copyright regime under the law No. 65-00. However, the exceptions do not follow the fair use or fair dealing model, therefore limiting the lawful use of copyrighted work by others. Arts. 30-44 list the exceptions, which include the reproduction of: news that have the character of mere press information; speeches made in deliberative assemblies or public meetings, works for educational or scientific purposes, among others.

It is reported that copyright infringement in the Dominican Republic, particularly through signal piracy, online distribution, and web‑based streaming, is widespread and remains insufficiently addressed by the government. Software piracy alone is estimated at approximately 75%.

The Dominican Republic has adopted the World Intellectual Property Organization (WIPO) Copyright Treaty.

The Dominican Republic has adopted the World Intellectual Property Organization (WIPO) Performances and Phonograms Treaty.

The Dominican Republic is a signatory of the World Trade Organization (WTO) Information Technology Agreement (ITA) of 1996, but is not a signatory of its 2015 expansion (ITA II).

Art. 61 of Law No. 47-25 establishes a sequencing requirement that prioritises nationally issued tenders and conditions recourse to international tendering upon the fulfilment of specified procedural thresholds, thereby functioning as a limitation on the immediate participation of foreign suppliers in public procurement. It stipulates that the call for a public tender may be issued at either the national or international level, with an international call required in any of the following circumstances: when the procurement falls under an agreement or treaty in force between the Dominican Republic and another State or a multilateral or bilateral credit organisation; when, on the basis of a market study and an accompanying technical report, it is determined that national bidders lack the capacity to supply the goods, provide the services, or execute the works in question; or when a nationally issued call has been declared void on two occasions due to non-compliant submissions or the absence of proposals, in which case a technical report must attest that enhanced efforts were made to notify and invite domestic suppliers. Notwithstanding the above, when a national call has been declared void twice, the contracting authority retains the power to issue further national calls.
Law No. 47‑25 repeals Law No. 340‑06, which establishes a similar restriction in Art. 16. The new legislation will take effect in January 2026.

Art. 172 of Law No. 47-25 stipulates that contracting institutions, when preparing their budget allocations, must reserve at least 30% of the funds designated for procurement for procedures exclusively intended for Micro, Small and Medium-sized Enterprises (MSMEs), allocating 20% to MSMEs in general and 10% to MSMEs led by women; furthermore, Art. 173 provides that procurement processes reserved for MSMEs shall require interested suppliers to have an established domicile within the municipal district, municipality, province, or region where the goods are to be supplied, the services rendered, or the works executed.
The preference regime in Law No. 47-25 differs somewhat from that in Law No. 488-08, which nevertheless remains in force. According to Art. 25, state institutions must reserve 15% of purchases of goods and services to national MSMEs. Moreover, Art. 26 establishes that when MSMEs are managed by women who have a shareholding or capital stock of more than 50%, then the percentage of purchases by state institutions reserved for MSMEs goes up to 20%.

Art. 12 of Decree-Law No. 22/2020 establishes a quantitative limitation on non-commercial imports by providing that the total value of the goods contained in each consignment may not exceed USD 200.

In June 2020, Cimex Corporation notified all users of the "tuenvio.cu" e-commerce platform via email about new regulations for online purchases. According to these updated regulations, users of the Tuenvio.cu platform, which facilitates e-commerce in Cuba, is limited to one purchase per day for food and toiletries combos. These restrictions were outlined in Cimex's online shopping guide, which is available on the Tuenvio.cu platform, ensuring customers were aware of the daily purchase limits.

There are no formal licensing requirements in Cuba in the electronic commerce sector. However, Cuba has only one online trading platform called Tuenvio.cu, which is managed by the state-owned company CIMEX. This, indirectly, represents a restriction that excludes foreign companies that want to seek licenses to manage an electronic commerce platform.